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BCG [Bacillus Calmette-Guérin] – (Immunotherapy for Bladder Cancer)

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BCG [Bacillus Calmette-Guérin] – (Immunotherapy for Bladder Cancer)

Introduction

BCG (Bacillus Calmette-Guérin) is a form of immunotherapy used to treat non-muscle invasive bladder cancer (NMIBC). By stimulating the body’s immune system, BCG helps prevent cancer recurrence and progression, making it a highly effective treatment for this type of bladder cancer.

Purpose

  • Treats non-muscle invasive bladder cancer (stages Ta, T1, and CIS).
  • Reduces the risk of cancer recurrence and progression.
  • Preserves bladder function while effectively managing cancer.

How It Works

BCG is a live, weakened strain of Mycobacterium bovis. When instilled into the bladder, it triggers an immune response that targets cancer cells, reducing their ability to grow and spread.

Usage

  • Administered directly into the bladder through a catheter (intravesical therapy) once weekly for 6 weeks (induction phase).
  • Maintenance therapy may follow with periodic treatments over several months to years, depending on individual response.
  • Each session requires holding the medication in the bladder for approximately 2 hours before voiding.

Considerations

  • Common side effects include bladder irritation, frequent urination, and mild flu-like symptoms.
  • Rare but serious side effects include systemic infection; patients are monitored closely for signs of complications.
  • Patients should avoid caffeine and excessive fluid intake on treatment days to minimize discomfort.

At Crossroads Urology

At Crossroads Urology, we specialize in administering BCG therapy as part of a comprehensive bladder cancer treatment plan. Our providers ensure patient comfort and safety while delivering this highly effective therapy.

Conclusion

BCG [Bacillus Calmette-Guérin] is a proven immunotherapy for managing non-muscle invasive bladder cancer, helping patients achieve excellent outcomes while preserving bladder function. Contact Crossroads Urology today to learn more about this life-saving treatment.